Kaposi’s varicelliform eruption is a rare and potentially fatal viral infection caused mainly by reactivation of herpes simplex virus. It concomitantly occurs with. Disseminated herpes or vaccinia in the setting of underlying skin diseases is known as Kaposi’s varicelliform eruption (KVE). Patients typically present with. It is autosomal dominant in transmission. Patients with DWD are prone to frequent superinfection including the rare complication of Kaposi varicelliform eruption.
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Create a free personal account to download free article PDFs, sign up for alerts, and more. PubMed Links to PubMed. Patient responded adequately to oral acyclovir therapy. Retrieved from ” https: National Center for Biotechnology InformationU.
Kapisi, Mathes et al. Questions To access free multiple choice questions on this topic, click here. Widespread clusters of vesicles and erosions covered by hemorrhagic crusts.
Kaposi’s Varicelliform Eruption | JAMA Dermatology | JAMA Network
Javetz, Melnick, and Adelberg’s Medical Microbiology. Abstract Kaposi’s varicelliform eruption is a rare and potentially fatal viral infection caused mainly by reactivation of herpes simplex virus. StatPearls Publishing; Jan. Histopathology A skin biopsy is not required to confirm a diagnosis, but if it is performed, histological findings include intra-epidermal blister, acantholysis, multinuclear giant cells with intranuclear inclusion, and ballooning degeneration of the keratinocytes.
We conducted a retrospective observational study that included 19 patients [ Table 1 ] between 0 and 55 years who were diagnosed with KVE between 01 March and 01 March Bestue M, Cordero A. Purchase access Subscribe to the journal.
N Am J Med Sci. The recurrent type occurs in adulthood and is usually a milder and more localized form, generally presenting without viremia.
Author information Copyright and License information Disclaimer. Nucleoside analogs are the antiviral agents most commonly used since they inhibit viral DNA replication. Patients with Kaposi varicelliform eruption present with a sudden skin eruption of painful clusters of umbilicated vesicles and pustules.
Kaposi’s varicelliform eruption: A case series
Eczema herpeticum in two elderly patients. Review Kaposi’s varicelliform eruption in a patient with healing second degree burns. The disease equally affects men and women and does not appear to have a specific ethnic predominance. Garg G, Thami GP. The Tzanck smear, viral cultures, skin biopsy, or detection of viral DNA by Polymerase Chain Reaction may be helpful in doubtful cases.
Kaposi’s varicelliform eruption: A case series
In addition, the varucelliform can be complicated by multiple organ involvements, mainly of the central nervous system, liver, lungs, gastrointestinal tract, and adrenal glands. To access free multiple choice questions on this topic, click here.
None, Conflict of Interest: Junctional adhesion molecule overexpression in Kaposi varicelliform eruption skin lesions – as a possible herpes virus entry site.
Create a personal account to register for email alerts with links to free full-text articles. The head was the most commonly involved site, followed by trunk and limbs.
It is more common in children, mainly because of its relationship with AD, although cases in healthy adults have also been reported. Merkel cell polyomavirus Merkel cell carcinoma.
Kaposi’s Varicelliform Eruption
The diagnosis is mainly clinical. The most varicellfiorm ophthalmological sequela is herpetic keratitis which may lead to vision loss resulting from corneal scarring. In fact, a histological examination may confirm a diagnosis that may not have been thought of clinically, whereas polymerase chain reaction will detect viral DNA by Polymerase Chain Reaction. However, the finding of cytoplasmic inclusion bodies in histological examination suggested a viral origin.
The available evidence indicates that the condition may be provoked by at least two viruses, either vaccinia or herpes simplex, the latter bring most frequently encountered. Affilations 1 Rabta Hospital.
KVE was first described by Moritz Kaposi in the 19 th century, who assumed it was a fungal infection, whereas Juliysber argued that it was caused by bacterias.
Kaposi’s varicelliform eruption associated baricelliform the use of varicellifork ointment in two neonates. This condition is most commonly caused by herpes simplex virus type 1 or 2, but may also be caused by coxsackievirus A16, or vaccinia virus. Fifteen were children and only four were adults, with a similar distribution in both sexes 9 females and 10 males. Eczema herpeticum is caused by Herpes simplex virus HV1, the virus that causes cold sores; it can also be caused by other related viruses.